Keratinizing Squamous Cell Carcinoma Secondary to Prosthetic Mesh. Case Report
DOI:
https://doi.org/10.26871/killcanasalud.v9i2.1640Keywords:
Squamous cell carcinoma, Postoperative complications, Surgical mesh, Ventral herniaAbstract
Introduction: The use of prosthetic meshes in hernia repair surgeries has revolutionized the management of abdominal wall defects. However, the rare occurrence of malignant neoplasms such as keratinizing squamous cell carcinoma (SCC), related to chronic inflammation induced by foreign bodies, represents an emerging clinical concern. Case report: A 53-year-old female with a complex surgical history and a recent diagnosis of gastric cancer presented with severe weight loss, enterocutaneous fistulas, and purulent secretions. Diagnostic evaluation confirmed an infiltrating keratinizing squamous cell carcinoma associated with a previously placed prosthetic mesh. The patient underwent subtotal gastrectomy, resection of the compromised mesh, and Roux-en-Y reconstruction. The postoperative course was complicated by hypovolemic shock and bile leakage, which required management in the intensive care unit and further surgical intervention. This case illustrates an extremely rare but clinically significant complication, highlighting the possible association between prosthesis-induced chronic inflammation and carcinogenesis. Conclusion: This report adds evidence to the limited literature on SCC associated with prosthetic mesh use and reinforces the importance of long-term clinical surveillance in patients with prosthetic implants. It also emphasizes the need for a multidisciplinary approach for the timely diagnosis and management of these unusual complications.
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