ASOCIACIÓN ENTRE EL SINDROME METABÓLICO Y SEVERIDAD DE LA PERIODONTITIS EN ADULTOS

Authors

  • July Vega-Martínez

DOI:

https://doi.org/10.26871/killcanasalud.v5i1.796

Abstract

The metabolic syndrome (MS) increases the risk of suffering from diseases such as diabetes mellitus and cardiovascular disease. The objective was to determine the association between the metabolic syndrome and the severity of periodontitis in adults. A case-control study was carried out with 80 medical records of adult patients (40 with metabolic syndrome and 40 healthy controls) of both sexes, treated at the endocrinology and metabolic diseases service of the HN-PNPLNS, Lima-Peru. The presence of MS indicators were evaluated such as an increase in abdominal circumference (AC), fasting glycemia (FG), blood pressure (BP), triglycerides (TG) and a decrease in HDL cholesterol (HDL-c); as well as periodontitis according to its severity, initial, moderate and severe; age and sex were controlled. The results showed that periodontitis occurred in 100% of the group with MS and only in 50% of the control group, 57.5% of the group with MS had initial periodontitis and 3 indicators (CA, FG, BP), the 25% had moderate periodontitis and 4 indicators (CA, FG, BP, TG), 17.5% had severe periodontitis and 5 indicators (CA, FG, BP, TG, HDL-c), the relationship was highly significant (p <0.0001 ) between periodontitis and MS, as well as between the severity of periodontitis and MS (p <0.0001). In conclusion, these results suggest that there is a significant relationship between metabolic syndrome and periodontitis; and that this relationship is highly significant as the severity of periodontitis increases and as a greater number of indicators of metabolic syndrome appear.

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References

Rochlani Y, Venkata N, Kovelamundi S MJ. Metabolic syndrome: pathophysiology, management, and modulation by natural compounds. Ther Adv Vaccines. 2017;11(8):215–25.

Saklayen M. The global epidemic of the metabolic syndrome. Curr Hypertens Rep. 2018;20(12):1–8.

Arbañil Hugo. Síndrome metabólico - Definición y prevalencia. Rev Peru Ginecol y Obstet. 2011;57(4):233–6.

Tonetti MS, Greenwell H, Kornman KS. Staging and grading of periodontitis: Framework and proposal of a new classification and case definition. J Periodontol. 2018;89.

James SL, Abate D, Abate KH, Abay SM, Abbafati C, Abbasi N, et al. Global, regional, and national incidence, prevalence, and years lived with disability for 354 Diseases and Injuries for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392(10159):1789–858.

Girano J, Robello J. Relación entre obesidad y enfermedad periodontal: revisión de la literatura. Horiz Médico. 2020;20(3):e1081.

Lamster IB, Pagan M. Periodontal disease and the metabolic syndrome. Int Dent J. 2017;67(2):67–77.

Caton J, Armitage G, Berglundh T, Chapple ILC, Jepsen S, S. Kornman K, et al. A new classification scheme for periodontal and peri-implant diseases and conditions – Introduction and key changes from the 1999 classification. J Clin Periodontol. 2018;45(March):S1–8.

Daudt L, Musskopf M, Méndez M, Remonti L, Leitão C, Gross J. et al. Association between metabolic syndrome and periodontitis: a systematic review and meta-analysis. Braz Oral Res. 2018; 32: e35.

Gomes-Filho I, das Mercês M, de Santana Passos-Soares J. Severity of Periodontitis and Metabolic Syndrome: Is There an Association? J Periodontol. 2016; 87(4): 357-366.

Gobin R, Tian D, Liu Q, Wang J. Periodontal Diseases and the Risk of Metabolic Syndrome: An Updated Systematic Review and Meta-Analysis. Front Endocrinol. 2020; 11:336.

Khader Y, Khassawneh B, Obeidat B. Periodontal status of patients with metabolic syndrome compared to those without metabolic syndrome. J Periodontol. 2008; 79:2048-2053.

Van Dyke T, Van Winkelhoff A. Infection and inflammatory mechanisms. J Clin Periodontol. 2013; 40(14): 1-7.

Preshaw P, Alba A, Herrera D, Jepsen S, Konstantinidis A, Makrilakis K. Periodontitis and diabetes: a two-way relationship. Diabetología. 2012; 55 (1): 21–3.

Colchado Jorge R. Alteraciones en la fagocitosis de los leucocitos creviculares de pacientes diabéticos con enfermedad periodontal. Odontol Sanmarquina. 2008;11(1):14–8.

Bullon P, Morillo J, Ramirez-Tortosa M. Metabolic syndrome and periodontitis: is oxidative stress a common link? J Dent Res. 2009; 88:503-518.

Thanakun S, Watanabe H, Thaweboon S, Izumi Y. Association of untreated metabolic syndrome with moderate to severe periodontitis in Thai population. J Periodontol. 2014; 85:1502-1514.

Zuk A, Quiñonez C, Lebenbaum M. The association between undiagnosed glycemic abnormalities and cardiometabolic risk factors with periodontitis: results from 2007-2009 canadian health measures survey. J Clin Periodontol. 2017; 44:132-141

D’Aiuto F, Sabbah W, Netuveli G. Association of the metabolic syndrome with severe periodontitis in a large U.S. populationbased survey. J Clin Endocrinol Metab. 2008; 93:3989-3994.

Nesbitt M, Reynolds MA, Shiau H, Choe K, Simonsick EM, Ferrucci L. Association of periodontitis and metabolic syndrome in the Baltimore Longitudinal Study of Aging. Aging Clin Exp Res. 2010; 22:238-242.

Han D, Shin H, Kim M. Group of serum inflammatory markers and periodontitis-metabolic syndrome coexistence in Koreans. J Periodontol. 2012; 83:612-620.

Kaye E, Chen N, Cabral H, Vokonas P, Garcia R. Metabolic Syndrome and Periodontal Disease Progression in Men. J Dent Res. 2016; 95(7): 822-828.

Alhabashneh R, Khader Y, Herra Z, et al. The association between periodontal disease and metabolic syndrome among outpatients with diabetes in Jordan. J Diabetes Metab Disord. 2015; 14:67

Li Y, Lu Z, Zhang X. Metabolic syndrome exacerbates inflammation and bone loss in periodontitis. J Dent Res. 2015; 94:362-370

Genco R, Grossi S, Ho A, Nishimura F, Murayama Y. A proposed model linking inflammation to obesity, diabetes, and periodontal infections. J Periodontol. 2005; 76(11): 2075–2084.

Fenesy K. Periodontal diseases: An overview for physicians. Mt Sinai J Med. 1998; 65:362–9.

Mohammadi M, Gozashti MH, Aghadavood M, Mehdizadeh MR, Hayatbakhsh MM. Clinical Significance of Serum IL-6 and TNF-α Levels in Patients with Metabolic Syndrome. Rep Biochem Mol Biol. 2017;6(1):74-79.

Gay I, Tran D, Cavender A, Weltman R, Chang J, Luckenbach E, et al. The effect of periodontal therapy on glycemic control in a hispanic population with type 2 diabetes: A randomized controlled trial. J Clin Periodontol. 2014; 41:673–80.

Gallagher E, Leroith D, Karnieli E. The metabolic syndrome--from insulin resistance to obesity and diabetes. Med Clin North Am. 2011; 95(5):855- 873

Published

2021-10-14
ESTADISTICAS
  • Abstract 342
  • DESCARGAR EN PDF (Español (España)) 181

How to Cite

Vega-Martínez, J. (2021). ASOCIACIÓN ENTRE EL SINDROME METABÓLICO Y SEVERIDAD DE LA PERIODONTITIS EN ADULTOS. Killkana Salud Y Bienestar, 5(1), 1–14. https://doi.org/10.26871/killcanasalud.v5i1.796

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Section

Artículos originales de investigación