Rash asociado a fármacos con eosinofilia y síntomas cutáneos. A propósito de un caso.
DOI:
https://doi.org/10.26871/killcanasalud.v7i1.1263Palabras clave:
Rash Cutaneo, Eosinofilia, Anticonvulsivantes, Reaccion Adversa a farmacosResumen
El Rash asociado a fármacos con eosinofilia y síntomas cutáneos conocido como síndrome DRESS, llamado por las iniciales inglesa, es una toxicodermia grave de etiología desconocida caracterizada por: fiebre, exantema, adenopatías, alteraciones hematológicas, afectación visceral y sistémica. Dada su gravedad y posible confusión con otras reacciones cutáneas medicamentosas, es importante establecer las relaciones causales y detectar los posibles fármacos implicados, además del diagnóstico diferencial por su compromiso dérmico y el tratamiento actualizado ante tal complicación.
El objetivo del presente artículo es describir un caso de Síndrome DRESS asociado a la administración de terapia anticonvulsivante que inicialmente se relacionó a una reacción de hipersensibilidad; el caso que se reporta es de una paciente de 36 años, atendida en consulta con tratamiento previo para Epilepsia, quien ingresa por reacción sistémica: compromiso dérmico, hepático y hematológico, esta patología fue tratada con terapia a base de corticoides, logrando la recidiva del cuadro clínico.
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