Killkana Salud y Bienestar

Keratinizing Squamous Cell Carcinoma Secondary to Prosthetic Mesh. Case Report

2025-07-01T21:24:17+00:00

Introduction: The use of prosthetic meshes in hernia repair surgeries has revolutionized the management of abdominal wall defects. However, the rare occurrence of malignant neoplasms such as keratinizing squamous cell carcinoma (SCC), related to chronic inflammation induced by foreign bodies, represents an emerging clinical concern. Case report: A 53-year-old female with a complex surgical history and a recent diagnosis of gastric cancer presented with severe weight loss, enterocutaneous fistulas, and purulent secretions. Diagnostic evaluation confirmed an infiltrating keratinizing squamous cell carcinoma associated with a previously placed prosthetic mesh. The patient underwent subtotal gastrectomy, resection of the compromised mesh, and Roux-en-Y reconstruction. The postoperative course was complicated by hypovolemic shock and bile leakage, which required management in the intensive care unit and further surgical intervention. This case illustrates an extremely rare but clinically significant complication, highlighting the possible association between prosthesis-induced chronic inflammation and carcinogenesis. Conclusion: This report adds evidence to the limited literature on SCC associated with prosthetic mesh use and reinforces the importance of long-term clinical surveillance in patients with prosthetic implants. It also emphasizes the need for a multidisciplinary approach for the timely diagnosis and management of these unusual complications.

Duodenal follicular lymphoma: cause or incidental finding of dyspepsia. Clinical case

2025-08-06T14:35:45+00:00

Introduction: Primary duodenal follicular lymphoma is a rare, low-grade B-cell neoplasm characterized by an indolent clinical course or by nonspecific symptoms and endoscopic findings. Most cases are diagnosed incidentally during endoscopic procedures. Objective: To describe a case of duodenal follicular lymphoma diagnosed in the context of nonspecific dyspeptic symptoms. Clinical case: A 54-year-old female patient with no relevant medical history presented with intermittent abdominal pain and distension of several years' duration. Due to the persistence of symptoms, an upper gastrointestinal video endoscopy was performed, which identified a mucosa with multiple whitish nodular elevations, with a granular appearance, distributed diffusely, with a cobblestone mucosal pattern and without evident alterations in the vascular pattern. The biopsy was compatible with follicular lymphoma, later confirmed by immunohistochemistry. Conclusion: Primary duodenal follicular lymphoma is a rare entity with a favorable prognosis. Early detection allows for a conservative approach in most cases. The correlation between endoscopic findings and histopathological studies is essential to avoid misdiagnoses and define appropriate management.

Ultrasound imaging findings in women with infertility: a literature review

2025-06-16T15:10:15+00:00

Introduction: Infertility represents a global health problem, affecting a considerable percentage of couples of reproductive age, generating various physical, emotional, and economic consequences. In this context, ultrasound emerges as a fundamental diagnostic tool due to its accessibility, non-invasive nature, and low cost. Objective: The main objective is to analyze the most relevant imaging findings obtained through ultrasound, in order to consolidate the existing evidence on the utility of this technique in the evaluation of female infertility. Methodology: A comprehensive literature review of 34 scientific articles published between the years 2020-2024 was carried out. The search was conducted in the Pubmed, Scopus, and Google Scholar databases, using a search strategy that combined health descriptors, such as: "Fertility female", "Ultrasonography", "Ecografía". Results: The literature review highlights the crucial role of ultrasound, particularly the transvaginal approach, in the evaluation of the anatomy and structures of the female reproductive system. It allows for the detection of various alterations such as ovarian cysts, uterine malformations, and pelvic adhesions. Additionally, it facilitates the monitoring of ovarian response and endometrial vascularization during assisted fertility treatments. Conclusion: Transvaginal ultrasound is established as a key diagnostic tool in the management of female infertility. Its value lies in its ability to provide relevant diagnostic and prognostic information, allowing for a personalized and comprehensive approach in the management of this condition. In case of limitations, it requires supplementation with other diagnostic techniques.

Therapeutic and industrial potential of plant enzymes: papain, bromelain, and ficin. A current review

2025-07-01T20:28:30+00:00

Proteolytic enzymes of plant origin, such as papain, bromelain, and ficin, have demonstrated a wide range of phytotherapeutic and technological applications. This article aims to describe their current uses in various fields such as medicine, dentistry, biotechnology, food industry, textiles, agriculture, and cosmetics, among others. Materials and methods: A literature review was conducted in the Scopus, Pubmed, MedLine, Scielo, Science Direct, and Google Scholar databases, without date restrictions, in English, Portuguese, and Spanish. DeCS/MeSH descriptors related to plant enzymes and phytotherapy were used, combined using the Boolean operators AND, OR, and NOT. After applying eligibility criteria, 35 articles were selected for analysis from a total of 80 identified articles. Results: The results show that these enzymes exhibit properties within the results; the enzymes studied have therapeutic properties (anti-inflammatory, bactericidal, bacteriostatic, antifungal, healing, mucolytic), which supports their use in clinical and surgical contexts. They also stand out in sectors such as medicine, dentistry, biotechnology, food, textiles, and cosmetics. Conclusion: It is concluded that these plant enzymes are a promising alternative for the development of sustainable therapeutic and technological products, with strong potential for future research.

Evaluation of risk factors associated with food safety in pregnant women: systematic review

2025-05-26T20:00:06+00:00

Introduction: Food security is essential for nutritional health, especially in pregnant women, as it affects both the mother and the development of the fetus. Adequate nutritional status during pregnancy prevents the development of complications such as anemia, preeclampsia, and low birth weight. Methodology: A systematic review of 28 studies published between 2019 and 2024 in English, Spanish, and Portuguese was conducted. Cohort, case-control, and cross-sectional studies were included. The search was conducted in the PubMed, Web of Science, Scopus, and Scielo databases. Results: It was found that food insecurity during pregnancy is associated with maternal-fetal health problems, including premature births and low birth weight. In addition, factors such as educational level, income, and ethnicity were associated with the level of food security of pregnant women. These determinants directly influence access to nutritious foods and reflect the need for public policies and support programs to improve food security in this vulnerable group. Conclusions: Adequate food security in pregnant women ensures healthy fetal development and prevents complications during pregnancy. Indeed, socioeconomic and educational determinants contribute to food insecurity.

Musculoskeletal Disorders and Burnout Syndrome in Dentistry Students Program at the Catholic University of Cuenca Campus Azogues, march-august 2024

2025-08-15T13:18:29+00:00

Dentistry students are exposed to improper postures, leading to musculoskeletal injuries that can result in loss of stability and body balance. These issues are exacerbated by prolonged postures, excessive force, repetitive movements, and an inadequate working environment. Additionally, both students and professionals in the dental field face challenges to their mental health due to the stress and demands of their work, which can lead to the development of Burnout Syndrome. Objective: To identify the musculoskeletal disorders and Burnout Syndrome associated with clinical practice in the dentistry students Program at the Catholic University of Cuenca, Campus Azogues, from March to August 2024. Methods: Observational, descriptive, cross-sectional study. The Nordic Kuorinka questionnaire and the Maslach Burnout Inventory (MBI) were applied to 198 students, after obtaining informed consent. Data analysis was performed using IBM SPSS Statistics v.27. Results: There was a prevalence of musculoskeletal disorders in the lumbar, dorsal, neck, and wrist regions. Regarding Burnout Syndrome participants demonstrated low levels of depersonalization, personal accomplishment, and emotional exhaustion. Conclusions: This study confirms a significant prevalence of Burnout Syndrome and musculoskeletal disorders among dentistry students at the Catholic University of Cuenca Campus Azogues.

Semiology of the environment: reading the body, listening to the context

2025-09-05T15:48:40+00:00

The semiology of the environment proposes integrating the interpretation of the body with critical listening to the patient's social, cultural, and environmental context. The body does not become ill in the abstract; each symptom expresses living conditions, family dynamics, work tensions, and structural inequalities. From a humanistic perspective, it is proposed that medical practice should transcend biomedical diagnosis to incorporate narratives, silences, and cultural knowledge that broaden the understanding of the health-illness process. Likewise, ethics and the doctor-patient relationship are highlighted as essential pillars of contemporary clinical practice, reaffirming medicine as a deeply human discipline where listening to the patient also implies listening to their history and context.